Kansas City Chiefs running back Isiah Pacheco is considered week-to-week after sustaining an MCL sprain in his right knee during the fourth quarter of the Chiefs' 28-7 victory over the Washington Commanders on October 27, 2025. Pacheco exited the game after taking a hard hit to his knee and did not return.
The MCL (medial collateral ligament) sprain occurred late in the game against Washington, marking another setback for the talented running back. This season, Pacheco has accumulated 329 rushing yards and one touchdown over eight games, along with 11 receptions for 43 yards and an additional touchdown.
With Pacheco sidelined, the Chiefs are expected to rely more heavily on their running back depth. Kareem Hunt, Elijah Mitchell, and Brashard Smith are all expected to see increased roles in the Chiefs' backfield during Pacheco's absence. The team will need to adjust their offensive strategy while their primary running back recovers.
This is not the first significant injury Pacheco has faced in his career. During Week 2 of the 2024 season, he suffered a fractured fibula in his right leg that sidelined him for several weeks. The current MCL sprain represents another challenge for the running back who has shown promise when healthy.
The timing of Pacheco's injury comes as the Chiefs face several important matchups in the coming weeks:
The Chiefs' ability to maintain their offensive production without Pacheco will be crucial as they navigate this stretch of their schedule. The team's medical staff will continue to monitor his recovery progress with the expectation that he could return to action in the coming weeks.
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